AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian Carcinoma

Epithelial ovarian cancer is the deadliest gynecological malignancy.The lack of effective treatments highlights the need for novel therapeutic interventions.The aim of this study was to investigate whether sustained adeno-associated virus (AAV) vector-mediated expression of vascular normalizing agents 3TSR and Fc3TSR and the antiangiogenic monoclon

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Microstructure and Mechanical Properties of Dissimilar Friction Stir Welding between Ultrafine Grained 1050 and 6061-T6 Aluminum Alloys

The ultrafine grained (UFGed) 1050 Al plates with a thickness of 2 mm, which were produced by the accumulative roll bonding technique after five cycles, were friction stir butt welded to 2 mm thick 6061-T6 Al alloy plates at a different revolutionary pitch that Kids clothes varied from 0.5 to 1.25 mm/rev.In the stir zone, the initial nano-sized lam

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Evaluation of Horticulture Based IFS Models for Providing Nutritional Security to Small and Marginal Farmers of Western Plain Zone of Uttar Pradesh, India

The farm holding size of India has been declining over years as a result of indiscriminate fragmentation of land holding, industrialization and urbanization.Small LIP SHINE BLUSH farm holders including the small and marginal farmers constitute more than 86% of Indian farm families.Under such situation horticulture plays a significant role in contri

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Noninvasive and quantitative measurement of C4d deposition for the diagnosis of antibody-mediated cardiac allograft rejectionResearch in context

Background: C4d is a specific biomarker for the diagnosis of antibody-mediated rejection (AMR) after cardiac transplantation.Although strongly recommended, routine C4d surveillance is hindered by the invasive nature of endomyocardial biopsy.Targeted ultrasound (US) has high sensitivity, and C4d is abundantly expressed VIRGIN COCONUT OIL within the

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